| Stuyvesant High School Lower Manhattan | 1497 | 99% |
| High School for Math, Science and Engineering at City College (HSMSE) Manhattanville | 1464 | 100% |
| New Explorations into Science, Technology and Math High School (NEST+m) Lower East Side | 1338 | 99% |
| Columbia Secondary School Morningside Heights | 1301 | 97% |
| Millennium High School Lower Manhattan | 1279 | 98% |
| Manhattan / Hunter Science High School Lincoln Square | 1250 | 96% |
| The Clinton School Chelsea-Union Sq | 1250 | 99% |
| N.Y.C. Lab School for Collaborative Studies Chelsea-Union Sq | 1226 | 99% |
| Eleanor Roosevelt High School Lenox Hill | 1212 | 99% |
| Fiorello H. LaGuardia High School of Music & Art and Performing Arts Lincoln Square | 1195 | 99% |
| Manhattan Center for Science and Mathematics East Harlem North | 1190 | 99% |
| Special Music School Lincoln Square | 1180 | 98% |
| Bard High School Early College Lower East Side | 1166 | 97% |
| High School for Dual Language and Asian Studies Chinatown | 1158 | 99% |
| N.Y.C. Museum School Chelsea-Union Sq | 1155 | 100% |
| West End Secondary School Lincoln Square | 1147 | 100% |
| Beacon High School Clinton | 1145 | 97% |
| Central Park East High School East Harlem South | 1138 | 99% |
| Manhattan Village Academy Chelsea-Union Sq | 1115 | 98% |
| NYC iSchool SoHo-Tribeca | 1114 | 98% |
| Institute for Collaborative Education (ICE) Gramercy | 1101 | 94% |
| Baruch College Campus High School Chelsea-Union Sq | 1096 | 100% |
| Park East High School East Harlem South | 1093 | 99% |
| Art and Design High School E. Midtown | 1076 | 96% |
| School of the Future High School Gramercy | 1037 | 98% |
| University Neighborhood High School Lower East Side | 1027 | 97% |
| Professional Performing Arts High School (PPAS) Clinton | 1026 | 99% |
| East Side Community School East Village | 1021 | 95% |
| Richard R. Green High School of Teaching Lower Manhattan | 1021 | 90% |
| Urban Assembly New York Harbor School Governors Island | 1013 | 94% |
| High School for Health Professions and Human Services Gramercy | 1006 | 95% |
| Orchard Collegiate Academy Lower East Side | 1003 | 93% |
| High School of Economics and Finance Lower Manhattan | 997 | 92% |
| Urban Assembly Gateway School for Technology Clinton | 993 | 100% |
| High School for Environmental Studies Clinton | 991 | 98% |
| Murray Hill Academy Murray Hill-Kips Bay | 984 | 88% |
| Quest to Learn Chelsea-Union Sq | 984 | 75% |
| Young Women's Leadership School (TYWLS) East Harlem South | 975 | 99% |
| Essex Street Academy Chinatown | 966 | 93% |
| Gramercy Arts High School Gramercy | 965 | 96% |
| Talent Unlimited High School Lenox Hill | 963 | 95% |
| Repertory Company High School for Theatre Arts Midtown | 962 | 98% |
| City College Academy of the Arts Washington Heights N. | 952 | 99% |
| Harvest Collegiate High School West Village | 952 | 84% |
| Urban Assembly Maker Academy Chinatown | 951 | 92% |
| Manhattan Early College School for Advertising Chinatown | 947 | 88% |
| Chelsea Career and Technical Education High School SoHo-Tribeca | 944 | 92% |
| Frank McCourt High School Upper West Side | 944 | 100% |
| Academy for Software Engineering (AFSE) Gramercy | 930 | 84% |
| Manhattan Bridges High School Clinton | 925 | 93% |
| A. Philip Randolph Campus High School Manhattanville | 922 | 68% |
| Humanities Preparatory Academy Chelsea-Union Sq | 922 | 100% |
| The High School for Language and Diplomacy Gramercy | 912 | 88% |
| The High School of Fashion Industries Chelsea-Union Sq | 912 | 95% |
| Pace High School Chinatown | 908 | 86% |
| Vanguard High School Lenox Hill | 908 | 88% |
| The Urban Assembly Academy of Government and Law Chinatown | 906 | 88% |
| Washington Heights Expeditionary Learning School (WHEELS) Washington Heights N. | 905 | 93% |
| Lower East Side Preparatory High School Chinatown | 903 | — |
| Jacqueline Kennedy Onassis High School Midtown | 902 | 91% |
| Manhattan Business Academy Chelsea-Union Sq | 901 | 90% |
| Frederick Douglass Academy Central Harlem North | 899 | 93% |
| Union Square Academy for Health Sciences Gramercy | 894 | 97% |
| Stephen T. Mather Building Arts & Craftsmanship High School Clinton | 891 | 89% |
| 47 The American Sign Language and English Secondary School Gramercy | 885 | 100% |
| City-As-School West Village | 883 | — |
| The Urban Assembly School of Design and Construction Clinton | 882 | 93% |
| High School of Arts and Technology Lincoln Square | 880 | 85% |
| The Urban Assembly Early College High School of Emergency Medicine Chinatown | 879 | 97% |
| Unity Center for Urban Technologies Murray Hill-Kips Bay | 879 | 94% |
| Wadleigh Secondary School for the Performing & Visual Arts Central Harlem South | 879 | 100% |
| Emma Lazarus High School for English Language Scholars Chinatown | 877 | — |
| The Urban Assembly School for Media Studies Lincoln Square | 874 | 93% |
| High School for Law, Advocacy and Community Justice Lincoln Square | 871 | 85% |
| Food and Finance High School Clinton | 868 | 92% |
| Leadership and Public Service High School Lower Manhattan | 868 | 91% |
| Lower Manhattan Arts Academy Chinatown | 868 | 82% |
| Community Health Academy of the Heights Washington Heights S. | 867 | 89% |
| The Global Learning Collaborative Upper West Side | 865 | 94% |
| New Design High School Chinatown | 864 | 96% |
| Inwood Early College for Health and Information Technologies Inwood | 863 | 84% |
| High School For Climate Justice Yorkville | 861 | 72% |
| Eagle Academy for Young Men of Harlem Central Harlem North | 858 | 78% |
| Hudson High School of Learning Technologies Chelsea-Union Sq | 855 | 83% |
| Urban Assembly School for the Performing Arts Manhattanville | 854 | 86% |
| Business of Sports School Clinton | 847 | 85% |
| Thurgood Marshall Academy for Learning and Social Change Central Harlem North | 840 | 88% |
| The Urban Assembly School for Global Commerce Central Harlem North | 837 | 80% |
| High School of Hospitality Management Clinton | 832 | 71% |
| The College Academy Washington Heights N. | 827 | 96% |
| Frederick Douglass Academy II Secondary School Central Harlem South | 823 | 81% |
| Landmark High School Chelsea-Union Sq | 820 | 84% |
| Murry Bergtraum High School for Business Careers Chinatown | 819 | 94% |
| High School for Law and Public Service Washington Heights N. | 817 | 79% |
| Edward A Reynolds Westside HS | 815 | — |
| The Urban Assembly School for Green Careers Upper West Side | 812 | 88% |
| Forsyth Satellite Academy Chinatown | 810 | — |
| The Heritage School East Harlem South | 808 | 91% |
| The Urban Assembly School of Business for Young Women Lower Manhattan | 801 | — |
| Manhattan International High School Lenox Hill | 799 | 85% |
| The Facing History School Clinton | 799 | 92% |
| Manhattan Academy for Arts & Language Murray Hill-Kips Bay | 791 | 88% |
| Esperanza Preparatory Academy East Harlem South | 787 | 78% |
| Mott Hall High School Central Harlem North | 776 | 91% |
| High School for Health Careers and Sciences Washington Heights N. | 767 | 91% |
| Liberty High School Academy for Newcomers Chelsea-Union Sq | 762 | — |
| High School for Media and Communications Washington Heights N. | 761 | 82% |
| High School for Excellence and Innovation Inwood | 752 | — |
| The James Baldwin School Chelsea-Union Sq | 752 | — |
| International High School at Union Square Gramercy | 732 | 85% |
| Independence High School Clinton | 727 | — |
| A School Without Walls: Hybrid Pathway | — | — |
| Gregorio Luperon High School for Science and Mathematics Washington Heights S. | — | 95% |
| Harvey Milk High School West Village | — | — |
| Mott Hall II | — | — |
| School for Global Leaders | — | — |